Spatial transcriptomics

Cancer Cell. 2022 Sep 12;40(9):895-900. doi: 10.1016/j.ccell.2022.08.021.

Abstract

Spatial transcriptomics, with other spatial technologies, has enabled scientists to dissect the organization and interaction of different cell types within the tumor microenvironment. We asked experts to discuss some aspects of this technology from revealing the tumor microenvironment and heterogeneity, to tracking tumor evolution, to guiding tumor therapy, to current technical challenges.

MeSH terms

  • Humans
  • Neoplasms* / genetics
  • Transcriptome*
  • Tumor Microenvironment / genetics