The tracts, cytoarchitecture, and neurochemistry of the spinal cord

Anat Rec (Hoboken). 2023 Apr;306(4):777-819. doi: 10.1002/ar.25079. Epub 2022 Sep 29.

Abstract

The human spinal cord can be described using a range of nomenclatures with each providing insight into its structure and function. Here we have comprehensively reviewed the key literature detailing the general structure, configuration of tracts, the cytoarchitecture of Rexed's laminae, and the neurochemistry at the spinal segmental level. The purpose of this review is to detail current anatomical understanding of how the spinal cord is structured and to aid researchers in identifying gaps in the literature that need to be studied to improve our knowledge of the spinal cord which in turn will improve the potential of therapeutic intervention for disorders of the spinal cord.

Keywords: Rexed laminae; cytoarchitecture; neuroanatomy; neurochemistry; spinal cord.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Neural Pathways
  • Neurochemistry*
  • Spinal Cord
  • Spine