Genitourinary Lesions Due to Monkeypox

Abstract

Background: Since May 2022, 31 000 cases of monkeypox infection have been reported in nonendemic areas.

Objective: To describe a series of cases of monkeypox with genitourinary involvement.

Design, setting, and participants: This was a prospective observational study of men diagnosed with monkeypox disease with genitourinary involvement.

Results and limitations: A total of 14 patients were recruited. The median age was 42 yr. Of these patients, 43% sought a consultation for genitourinary symptomatology, and 71% had engaged in sex with other men. Eight patients (57%) were positive for human immunodeficiency virus, one diagnosed synchronously; the remainder had a median CD4 count of 663/μl. Six patients (43%) had a different sexually transmitted disease. Penile oedema was present in 43% of patients and two patients required surgical exploration.

Conclusions: Genitourinary involvement is frequent in monkeypox disease and is often the reason for the consultation visit.

Patients summary: In this report we looked at how monkeypox disease can affect the genitourinary area, causing swelling of the penis or skin lesions.

Keywords: Genitourinary lesions; Monkeypox disease; Penile oedema.