Pseudophakic pupillary block after phacoemulsification and posterior chamber intraocular lens implantation: Cause identification and treatment refinement

Photodiagnosis Photodyn Ther. 2022 Dec:40:103109. doi: 10.1016/j.pdpdt.2022.103109. Epub 2022 Sep 9.

Abstract

Background: Pseudophakic pupillary block (PPB) was rare in patients who undergo phacoemulsification and posterior chamber intraocular lens (PCIOL) implantation. Laser peripheral iridotomy was the most reported but ineffective treatment in the literature.

Methods: Retrospective, interventional case series of patients who developed PPB in Taipei Veterans General Hospital from 2017 to 2021. Clinical course, diagnostic methods, treatment and outcomes were recorded and discussed.

Results: Four eyes of three patients were documented. All of them had diabetes and diabetic retinopathy. Anterior segment Optical coherence tomography (OCT) of these patients showed an exudative membrane at the peripapillary area while slit lamp image could not provide a clear view due to the severely edematous corneal condition. Laser peripheral iridotomy and yttrium aluminum garnet (YAG) laser aiming to the peripapillary exudation were applied to break the PPB successfully.

Conclusion: Diabetes mellitus, intravitreal injection and inflammation are crucial risk factors for PPB. Anterior segment OCT can be a useful diagnostic tool for the detection of the peripapillary exudative membrane while corneal clarity is compromised due to high intraocular pressure. In addition to peripheral laser iridotomy, an effective approach to resolve PPB may be the use of the YAG laser to break the exudative membrane.

Keywords: Laser iridotomy; Optical coherence tomography; Phacoemulsification; Posterior chamber intraocular lens; Pseudophakic pupillary block.

MeSH terms

  • Humans
  • Laser Therapy* / methods
  • Lens Implantation, Intraocular / adverse effects
  • Phacoemulsification* / adverse effects
  • Photochemotherapy* / methods
  • Pupil Disorders* / diagnosis
  • Pupil Disorders* / etiology
  • Pupil Disorders* / surgery
  • Retrospective Studies