Body hydration is considered one of the most important physiological parameters to measure and one of the most challenging. Current methods to assess hydration are invasive and require costly clinical settings. The bio-impedance analysis offers a noninvasive and inexpensive tool to assess hydration, and it can be designed to be used in wearable health devices. The use of wearable electronics in healthcare applications has received increased attention over the last decade. New, emerging medical devices feature continuous patient monitoring and data collection to provide suitable treatment and preventive actions. In this paper, a model of human skin is developed and simulated to be used as a guide to designing a dehydration monitoring system based on a bio-impedance analysis technique. The study investigates the effect of applying different frequencies on the dielectric parameters of the skin and the resulting measured impedance. Two different interdigitated electrode designs are presented, and a comparison of the measurements is presented. The rectangular IDE is printed and tested on subjects to validate the bio-impedance method and study the interpretation of its results. The proposed design offers a classification criterion that can be used to assess dehydration without the need for a complex mathematical model. Further clinical testing and data are needed to refine and finalize the criteria.
Keywords: COMSOL Multiphysics; bio-impedance analysis; hydration assessment; inkjet printing; interdigitated electrode; wearable devices.