Personality Disorders as a Possible Moderator of the Effects of Relational Interventions in Short-Term Psychoanalytic Psychotherapy with Depressed Adolescents

Int J Environ Res Public Health. 2022 Sep 2;19(17):10952. doi: 10.3390/ijerph191710952.

Abstract

A significant proportion of adolescents suffering from major depressive disorder (MDD) are likely to have a co-morbid personality disorder (PD). Short-term psychoanalytic psychotherapy (STPP) was found to be one treatment of choice for adolescents suffering from MDD.

Background: The first experimental study of transference work-in teenagers (FEST-IT) demonstrated the efficaciousness of transference work in STPP with adolescents suffering from MDD. The usefulness of STPP may be enhanced by exploring possible moderators.

Methods: Depressed adolescents (N = 69), aged 16-18 years, were diagnosed with the structured interview for DSM-IV PDs and randomized to 28 weeks of STPP with or without transference work. A mixed linear model was applied. The moderator effect was investigated by a three-way interaction including "time", "treatment group" and "number of PD criteria".

Results: A small but significant moderator effect was found for cluster B personality pathology. Patients with a higher number of cluster B PD criteria at baseline did better up to one-year post-treatment where therapists encouraged patients to explore the patient-therapist relationship in the here and now.

Conclusion: When treated with psychoanalytic psychotherapy for MDD, adolescents with cluster B PD symptoms seem to profit more from transference work than adolescents without such pathology.

Keywords: adolescent; depression; personality disorder; psychoanalytic psychotherapy; psychodynamic; transference.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Depressive Disorder, Major* / therapy
  • Diagnostic and Statistical Manual of Mental Disorders
  • Humans
  • Personality Disorders / diagnosis
  • Personality Disorders / therapy
  • Psychotherapy
  • Psychotherapy, Brief*
  • Treatment Outcome

Grants and funding

This research was funded by Vestfold Hospital Trust, The University of Oslo, Oslo University Hospital, The MRK Foundation and Josef and Haldis Andresens Legat. The funders of the study had no role in study design, data collection, data analysis, data interpretation, or writing of the report. The corresponding author had full access to all the data in the study and had final responsibility for the decision to submit for publication.