The Pictorial Screening Memory Test (P-MIS) for Adults with Moderate Intellectual Disability and Alzheimer's Disease

Emili Rodríguez-Hidalgo; Javier García-Alba; Maria Buxó; Ramon Novell; Susana Esteba-Castillo

doi:10.3390/ijerph191710780

The Pictorial Screening Memory Test (P-MIS) for Adults with Moderate Intellectual Disability and Alzheimer's Disease

Int J Environ Res Public Health. 2022 Aug 30;19(17):10780. doi: 10.3390/ijerph191710780.

Authors

Emili Rodríguez-Hidalgo¹, Javier García-Alba², Maria Buxó³, Ramon Novell^{1

3}, Susana Esteba-Castillo^{1

3}

Affiliations

¹ Specialized Service in Mental Health and Intellectual Disability, Institute of Health Assistance, Parc Hospitalari Martí i Julià, Catalonia, 17190 Girona, Spain.
² Research and Psychology in Education Department, Complutense University of Madrid, 28040 Madrid, Spain.
³ Neurodevelopmental Group [Girona Biomedical Research Institute]-IDIBGI, Institute of Health Assistance (IAS), Parc Hospitalari Martí i Julià, Catalonia, 17190 Girona, Spain.

Abstract

In this study, we examined normative data and diagnostic accuracy of a pictorial screening test to detect memory impairment for mild cognitive impairment (MCI) and Alzheimer's disease (AD) in Spanish-speaking adults with intellectual disability (ID). A total of 94 volunteers with ID (60 controls, 17 MCI, and 17 AD), were evaluated by neuropsychological tests including the PMIS-ID in a cross-sectional validation study. Discriminative validity between the MCI, AD, and control group was analyzed by the area under the ROC curve. A cut-off score of 4.5 on the immediate recall trial had a sensitivity of 69% and a specificity of 80% to detect memory impairment (AUC = 0.685; 95% CI = 0.506-0.863) in the AD group. The PMIS-ID is a useful screening test to rule out a diagnosis of memory decline in people with moderate level of ID and AD, and it shows good psychometric properties.

Keywords: Alzheimer’s disease; dementia intellectual disability; memory; mild cognitive impairment; screening.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alzheimer Disease* / diagnosis
Alzheimer Disease* / psychology
Cognitive Dysfunction* / diagnosis
Cognitive Dysfunction* / psychology
Cross-Sectional Studies
Humans
Intellectual Disability* / diagnosis
Neuropsychological Tests
ROC Curve
Sensitivity and Specificity

Grants and funding

This research was funded by the Spanish Government, grant number PI12/02019, PSI-2014-53524-P. The APC was funded by R.N.’s SESMDI research start-up funds.