Functional role of DNMT1 in the anti-leukemic effects of hypomethylating agents in AML cells

Leuk Res. 2022 Oct:121:106944. doi: 10.1016/j.leukres.2022.106944. Epub 2022 Sep 1.

Authors

Lin Li¹, Xiaoyan Hu¹, Jewel Nkwocha¹, Kanika Sharma¹, Liang Zhou¹, Steven Grant²

Affiliations

¹ Division of Hematology/Oncology, Department of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
² Division of Hematology/Oncology, Department of Medicine, Virginia Commonwealth University, Richmond, VA, USA; Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: steven.grant@vcuhealth.org.

PMID: 36075160
DOI: 10.1016/j.leukres.2022.106944

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural

MeSH terms

DNA (Cytosine-5-)-Methyltransferase 1* / genetics
Humans
Leukemia, Myeloid, Acute* / drug therapy
Leukemia, Myeloid, Acute* / genetics

Substances

DNA (Cytosine-5-)-Methyltransferase 1
DNMT1 protein, human

Grants and funding