Microsurgical arterial anastomosis in young and adult rats: an evolutive and comparative study

Acta Cir Bras. 2022 Sep 5;37(6):e370604. doi: 10.1590/acb370604. eCollection 2022.

Abstract

Purpose: To evaluate the caliber of an arterial micro-anastomosis in the young growing animal using a continuous suture technique. Additionally, late morphological changes and blood flows distal to the anastomosis were evaluated.

Methods: Seventy-four Wistar rats were submitted to laparotomy to access the aorta for blood flow measurement. The aorta was sectioned using microsurgery technique and an end-to-end anastomosis with continuous suture. After a period of six months to one year, the anastomosis was checked.

Results: Regarding the size of the aortas, comparing the pre- and postoperative values, there was an increase of 13.33% in adult animals and 25% in young animals, without any difference in the blood flows.

Conclusions: The arteries of young rats show signs of growth at the site of the anastomosis performed with continuous suture.

MeSH terms

  • Anastomosis, Surgical / methods
  • Animals
  • Arteries* / surgery
  • Microsurgery* / methods
  • Rats
  • Rats, Wistar
  • Suture Techniques
  • Vascular Surgical Procedures