Ultra-processed Foods and Cardiometabolic Health Outcomes: from Evidence to Practice

Curr Atheroscler Rep. 2022 Nov;24(11):849-860. doi: 10.1007/s11883-022-01061-3. Epub 2022 Sep 7.

Abstract

Purpose of review: Poor diet quality is the leading risk factor related to the overall cardiometabolic disease burden in the USA and globally. We review the current evidence linking ultra-processed foods and cardiometabolic health risk and provide recommendations for action at the clinical and public health levels.

Recent findings: A growing body of evidence conducted in a variety of study populations supports an association between ultra-processed food intake and increased risk of metabolic syndrome, hypertension, type 2 diabetes, overweight and obesity trajectories, and cardiovascular disease. The strongest evidence is observed in relation to weight gain and obesity among adults, as this association is supported by high-quality epidemiological and experimental evidence. Accumulating epidemiologic evidence and putative biological mechanisms link ultra-processed foods to cardiometabolic health outcomes. The high intake of ultra-processed foods in all population groups and its associated risks make ultra-processed foods an ideal target for intensive health promotion messaging and interventions.

Keywords: Cardiovascular disease; Diet quality; Dietary guidelines; NOVA; Obesity; Processed food; Type 2 diabetes.

Publication types

  • Review

MeSH terms

  • Adult
  • Cardiovascular Diseases* / epidemiology
  • Cardiovascular Diseases* / etiology
  • Cardiovascular Diseases* / prevention & control
  • Diabetes Mellitus, Type 2* / epidemiology
  • Diabetes Mellitus, Type 2* / etiology
  • Diet / adverse effects
  • Energy Intake
  • Fast Foods / adverse effects
  • Humans
  • Obesity / epidemiology