Intriguing diverse chemistry and unique molecular mechanisms: new medicines with diverse pharmacological activities from cephalopods ink

Nat Prod Res. 2023 Jun;37(11):1909-1916. doi: 10.1080/14786419.2022.2119567. Epub 2022 Sep 6.

Abstract

The ink that cephalopods secrete to hide and frighten the enemies contains a treasury rich in bioactive diverse compounds like DOPA, melanin, melanin synthase, tyrosinase, angiotensin converting enzyme, catecholamines, oligopeptides, polyphenols, flavonoids, alkaloids, polysaccharides, fatty acids and minerals. These groups of the aforementioned compounds have promising unique in-vitro and in-vivo biological activities like antioxidant activity, anti-inflammatory, vasopressin, anti-Parkinson, anti-cancer, anti-coagulant, antimicrobial, anti-retroviral, anti-ulcerogenic and immune boosting activities. Cephalopods ink can be offered in its raw state or after separation and purification of its chemical constituents for use as natural medicine to treat many diverse diseases.

Keywords: Cephalopods ink; chemistry; medicine.

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / pharmacology
  • Cephalopoda*
  • Ink
  • Melanins
  • Plant Extracts
  • Polyphenols

Substances

  • Melanins
  • Anti-Inflammatory Agents
  • Polyphenols
  • Plant Extracts