Bringing natural killer cells to the clinic

J Exp Med. 2022 Oct 3;219(10):e20220830. doi: 10.1084/jem.20220830. Epub 2022 Sep 6.

Abstract

Cancer is a leading cause of mortality worldwide, with around 10 million deaths every year. Despite huge advances due to immunotherapy, the majority of cancer patients present primary or secondary resistance to these treatments. In this Found in Translation, we focus on the approaches developed to harness the anti-tumor function of NK cells, suggesting promising strategies to complete the therapeutic arsenal of cancer immunotherapies.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Immunologic Factors
  • Immunotherapy
  • Killer Cells, Natural* / pathology
  • Neoplasms* / pathology
  • Neoplasms* / therapy

Substances

  • Immunologic Factors