Imaging of Pancreatic Ductal Adenocarcinoma: An Update on Recent Advances

Can Assoc Radiol J. 2023 May;74(2):351-361. doi: 10.1177/08465371221124927. Epub 2022 Sep 5.

Abstract

Pancreatic ductal carcinoma (PDAC) is one of the leading causes of cancer-related death worldwide. Computed tomography (CT) remains the primary imaging modality for diagnosis of PDAC. However, CT has limitations for early pancreatic tumor detection and tumor characterization so that it is currently challenged by magnetic resonance imaging. More recently, a particular attention has been given to radiomics for the characterization of pancreatic lesions using extraction and analysis of quantitative imaging features. In addition, radiomics has currently many applications that are developed in conjunction with artificial intelligence (AI) with the aim of better characterizing pancreatic lesions and providing a more precise assessment of tumor burden. This review article sums up recent advances in imaging of PDAC in the field of image/data acquisition, tumor detection, tumor characterization, treatment response evaluation, and preoperative planning. In addition, current applications of radiomics and AI in the field of PDAC are discussed.

Keywords: computer-assisted; deep learning; image processing; pancreatic neoplasms; radiomics; texture analysis.

Publication types

  • Review

MeSH terms

  • Artificial Intelligence
  • Carcinoma, Pancreatic Ductal*
  • Humans
  • Pancreatic Neoplasms* / pathology
  • Tomography, X-Ray Computed / methods