Primary sclerosing cholangitis: review for radiologists

Abstract

Primary sclerosing cholangitis is a rare chronic inflammatory disease affecting the bile ducts, which can eventually result in bile duct strictures, cholestasis and cirrhosis. Patients are often asymptomatic but may present with clinical features of cholestasis. Imaging plays an important role in the diagnosis and management. This review covers the pathophysiology, clinical features, imaging findings as well as methods of surveillance and post-transplant appearance.

Keywords: Biliary; Cholangitis; Elastography; Liver; MRI; Primary sclerosing cholangitis.