COVID-19 Vaccine-Related Adverse Events in Solid Cancer Patients Treated with Immunotherapy

Cancer Invest. 2022 Oct;40(9):760-766. doi: 10.1080/07357907.2022.2121966. Epub 2022 Sep 14.

Abstract

Little data are available regarding the effects of COVID-19 vaccine in cancer patients undergoing immunotherapy. Thereby, COVID-19 vaccine-related adverse events were monitored through a short questionnaire in solid cancer patients receiving immunotherapy. A total of 95 patients were included in this study. Two doses of vaccines were administered to cancer patients which mainly received Pembrolizumab (51.1%). Respectively 78.2% and 62.2% of patients reported no adverse events after the first and the second dose regardless of the type of vaccine used. Considering the high mortality rate due to COVID-19 among cancer patients, this study demonstrated the good tolerance of COVID-19 vaccine.

Keywords: COVID-19 vaccines; adverse events; cancer; immunotherapy.

MeSH terms

  • COVID-19 Vaccines* / adverse effects
  • COVID-19* / prevention & control
  • Humans
  • Immunotherapy
  • Neoplasms* / drug therapy

Substances

  • COVID-19 Vaccines