The potential role of the mobile and non-coding genomes in adaptive response

Alice M Godden; Simone Immler

doi:10.1016/j.tig.2022.08.006

The potential role of the mobile and non-coding genomes in adaptive response

Trends Genet. 2023 Jan;39(1):5-8. doi: 10.1016/j.tig.2022.08.006. Epub 2022 Sep 1.

Authors

Alice M Godden¹, Simone Immler²

Affiliations

¹ School of Biological Sciences, University of East Anglia, Norwich, NR4 7TJ, UK. Electronic address: alice.godden@uea.ac.uk.
² School of Biological Sciences, University of East Anglia, Norwich, NR4 7TJ, UK. Electronic address: s.immler@uea.ac.uk.

PMID: 36058789
DOI: 10.1016/j.tig.2022.08.006

Abstract

The tightly regulated feedback loops linking small RNAs (sRNAs) and transposable elements (TEs) offer the opportunity for an adaptive response to changing environments at the molecular level. Environmentally induced changes in TE and sRNA profiles may affect expression of coding genes and trigger an organismic and transgenerational response. Understanding this link may provide a mechanistic explanation for how species can adapt to changing climates and may offer novel molecular targets for biomedical and agricultural applications.

Keywords: epigenetic; germ cells; miRNAs; piRNAs; transposable elements.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

DNA Transposable Elements* / genetics
RNA, Small Interfering / genetics

Substances

RNA, Small Interfering
DNA Transposable Elements