Sagittal alignment of the cervical spine: radiographic analysis of 111 asymptomatic adolescents, a retrospective observational study

Yanjie Zhu; Xinkun Zhang; Yunshan Fan; Zhi Zhou; Guangfei Gu; Chuanfeng Wang; Chaobo Feng; Jia Chen; Shisheng He; Haijian Ni

doi:10.1186/s12891-022-05792-x

Sagittal alignment of the cervical spine: radiographic analysis of 111 asymptomatic adolescents, a retrospective observational study

BMC Musculoskelet Disord. 2022 Sep 3;23(1):840. doi: 10.1186/s12891-022-05792-x.

Authors

Yanjie Zhu^{1

2}, Xinkun Zhang^{1

2}, Yunshan Fan^{1

2}, Zhi Zhou^{1

2}, Guangfei Gu^{1

2}, Chuanfeng Wang^{1

2}, Chaobo Feng^{1

2}, Jia Chen^{1

2}, Shisheng He^{3

4}, Haijian Ni^{5

6}

Affiliations

¹ Orthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
² Spinal Pain Research Institute, Tongji University School of Medicine, Shanghai, China.
³ Orthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China. hss7418@tongji.edu.cn.
⁴ Spinal Pain Research Institute, Tongji University School of Medicine, Shanghai, China. hss7418@tongji.edu.cn.
⁵ Orthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China. nihaijianch@163.com.
⁶ Spinal Pain Research Institute, Tongji University School of Medicine, Shanghai, China. nihaijianch@163.com.

Abstract

Purpose: To describe the cervical spine morphology and explore its relationship to global sagittal alignment parameters in the asymptomatic adolescent population. METHODS: A total of 111 adolescent subjects were included. Sagittal alignment parameters, including C7 Slope, C2-C7 Cobb, C2-7 plumb line (PL), C2-S1 Sagittal Vertical Axis (SVA), C7-S1 SVA, T5-12 Cobb, T10-L2 Cobb, L1-S1 Cobb, pelvic incidence (PI), pelvic tilt (PT) and sacral slope (SS), were obtained from lateral radiographs. RESULTS: Forty-four males and sixty-seven females with a mean age of 16.12 ± 2.40 years were included in this study. The mean values of C7 Slope, C2-7 Cobb and C2-7PL were 20.45 ± 8.88°, -7.72 ± 12.10°, and 13.53 ± 11.63 mm, respectively. C2-7 Cobb, C7 Slope showed significant differences between the male and female groups. Correlation analysis showed that C7 slope was significantly correlated with C2-7 Cobb (r = -0.544, P < 0.001), C2-S1 SVA (r = 0.335, P < 0.001), and C7-S1 SVA (r = 0.310, P = 0.001), but not lumbosacral parameters(L5-S1 Cobb, PI, PT, SS). Using a modified method of Toyama to describe the cervical spine morphology, there were 37 cases (33.3%) in the Lordotic group, and C7 slope, C2-7 Cobb and C2-7PL showed significant differences between groups. According to C2-C7 Cobb, there were 80 Lordotic cases (72.1%). C7 slope and C2-7PL were significantly different between the two groups.

Conclusion: The cervical spine morphology of asymptomatic adolescents varies widely, from lordotic to kyphotic. Combining different classification methods provides a better understanding of the morphology of the cervical spine. C7 slope is an important predictor of global sagittal balance and C2-7PL is a key parameter for restoring cervical lordosis, which should be considered pre-operatively and for conservative treatment. Cervical regional sagittal alignment parameters are not correlated with lumbosacral parameters, and C2-7 Cobb, C7 Slope showed significant differences between males and females.

Keywords: Asymptomatic adolescent; C2-7 Cobb; C2-7 plumb line; C7 Slope; Cervical morphology; Sagittal alignment parameter.

Publication types

Observational Study

MeSH terms

Adolescent
Cervical Vertebrae / diagnostic imaging
Cervical Vertebrae / surgery
Female
Humans
Kyphosis* / surgery
Lordosis* / diagnostic imaging
Lordosis* / surgery
Lumbar Vertebrae / surgery
Male
Retrospective Studies
Sacrum