A tunable genome editing system of the prime editor mediated by dihydrofolate reductase

Affiliations

• ¹ Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China; Department of Ophthalmology, Shanghai Changhai Hospital, Shanghai 200043, China.
• ² Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.
• ³ Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China; Shanghai Key Laboratory of Ocular Fundus Diseases, 100 Haining Road, Shanghai 200080, China.
• ⁴ Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China; Shanghai Key Laboratory of Ocular Fundus Diseases, 100 Haining Road, Shanghai 200080, China. Electronic address: xiaosa.li@shgh.cn.