Early diagnosis of symptomatic ovarian cancer in primary care in the UK: opportunities and challenges

Prim Health Care Res Dev. 2022 Sep 2:23:e52. doi: 10.1017/S146342362200041X.

Abstract

Background: Ovarian cancer is the sixth most common cause of cancer-related death in the UK amongst women. Ovarian cancer presents particular challenges for general practitioners (GPs) to diagnose due to its rarity and presentation with non-specific symptoms.

Methods: A narrative overview of the literature was conducted by searching PubMed and Researchgate for relevant articles, using keywords such as "ovarian cancer," "primary care" and "diagnosis."

Results and discussion: Studies have shown that in the UK, GPs have a lower readiness to refer and investigate potential cancer symptoms compared with their international counterparts; and this has been correlated with reduced survival. Early diagnosis can be facilitated through a people-focussed and system-based approach which involves both educating GPs and using risk algorithms, rapid diagnostic centres/multi-disciplinary centres and being data-driven through the identification of best practice from national audits. Further research is required into the best evidence-based early investigations for ovarian cancer and more effective biomarkers.

Keywords: UK; community health services; early diagnosis; ovarian neoplasms; primary health care; women’s health.

MeSH terms

  • Early Detection of Cancer
  • Female
  • General Practitioners*
  • Humans
  • Ovarian Neoplasms* / diagnosis
  • United Kingdom