Bibliometric and visual analysis of intestinal ischemia reperfusion from 2004 to 2022

Yantong Wan; Peng Dong; Xiaobing Zhu; Yuqiong Lei; Junyi Shen; Weifeng Liu; Kexuan Liu; Xiyang Zhang

doi:10.3389/fmed.2022.963104

Bibliometric and visual analysis of intestinal ischemia reperfusion from 2004 to 2022

Front Med (Lausanne). 2022 Aug 15:9:963104. doi: 10.3389/fmed.2022.963104. eCollection 2022.

Authors

Yantong Wan¹, Peng Dong¹, Xiaobing Zhu², Yuqiong Lei³, Junyi Shen⁴, Weifeng Liu³, Kexuan Liu³, Xiyang Zhang³

Affiliations

¹ College of Anesthesiology, Southern Medical University, Guangzhou, China.
² Department of Anesthesiology, Hospital of Traditional Chinese Medicine of Zhongshan City, Zhongshan, China.
³ Department of Anesthesiology, Nan Fang Hospital, Southern Medical University, Guangzhou, China.
⁴ The Second Clinical Medical College, Southern Medical University, Guangzhou, China.

Abstract

Background: Intestinal ischemia/reperfusion (I/R) injury is a common tissue-organ damage occurring in surgical practice. This study aims to comprehensively review the collaboration and impact of countries, institutions, authors, subject areas, journals, keywords, and critical literature on intestinal I/R injury from a bibliometric perspective, and to assess the evolution of clustering of knowledge structures and identify hot trends and emerging topics.

Methods: Articles and reviews related to intestinal I/R were retrieved through subject search from Web of Science Core Collection. Bibliometric analyses were conducted on Excel 365, CiteSpace, VOSviewer, and Bibliometrix (R-Tool of R-Studio).

Results: A total of 1069 articles and reviews were included from 2004 to 2022. The number of articles on intestinal I/R injury gradually plateaued, but the number of citations increased. These publications were mainly from 985 institutions in 46 countries, led by China and the United States. Liu Kx published the most papers, while Chiu Cj had the largest number of co-citations. Analysis of the journals with the most outputs showed that most journals focused on surgical sciences, cell biology, and immunology. Macroscopic sketch and microscopic characterization of the entire knowledge domain were achieved through co-citation analysis. The roles of cell death, exosomes, intestinal flora, and anesthetics in intestinal I/R injury are the current and developing research focuses. The keywords "dexmedetomidine", "proliferation", and "ferroptosis" may also become new trends and focus of future research.

Conclusion: This study comprehensively reviews the research on intestinal I/R injury using bibliometric and visualization methods, and will help scholars better understand the dynamic evolution of intestinal I/R injury and provide directions for future research.

Keywords: CiteSpace; VOSviewer; bibliometric; intestinal ischemia reperfusion; visual analysis.