Application of antimicrobial, potential hazard and mitigation plans

Shing Ching Khoo; Meng Shien Goh; Amirah Alias; Vijitra Luang-In; Kah Wei Chin; Tiong Hui Ling Michelle; Christian Sonne; Nyuk Ling Ma

doi:10.1016/j.envres.2022.114218

Application of antimicrobial, potential hazard and mitigation plans

Environ Res. 2022 Dec;215(Pt 1):114218. doi: 10.1016/j.envres.2022.114218. Epub 2022 Aug 29.

Authors

Shing Ching Khoo¹, Meng Shien Goh¹, Amirah Alias², Vijitra Luang-In³, Kah Wei Chin⁴, Tiong Hui Ling Michelle⁴, Christian Sonne⁵, Nyuk Ling Ma⁶

Affiliations

¹ Henan Province Engineering Research Centre for Biomass Value-added Products, School of Forestry, Henan Agricultural University, Zhengzhou, 450002, China; BIOSES Research Interest Group, Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, 21030, Kuala Nerus, Terengganu, Malaysia.
² Eco-Innovation Research Interest Group, Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, 21030, Kuala Nerus, Terengganu, Malaysia.
³ Natural Antioxidant Innovation Research Unit, Department of Biotechnology, Faculty of Technology, Mahasarakham University, Khamriang, Kantarawichai, Maha Sarakham, 44150, Thailand.
⁴ BIOSES Research Interest Group, Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, 21030, Kuala Nerus, Terengganu, Malaysia.
⁵ Henan Province Engineering Research Centre for Biomass Value-added Products, School of Forestry, Henan Agricultural University, Zhengzhou, 450002, China; Aarhus University, Department of Bioscience, Arctic Research Centre (ARC), Frederiksborgvej 399, PO Box 358, DK-4000, Roskilde, Denmark. Electronic address: cs@bios.au.dk.
⁶ Henan Province Engineering Research Centre for Biomass Value-added Products, School of Forestry, Henan Agricultural University, Zhengzhou, 450002, China; BIOSES Research Interest Group, Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, 21030, Kuala Nerus, Terengganu, Malaysia. Electronic address: nyukling@umt.edu.my.

Abstract

The tremendous rise in the consumption of antimicrobial products had aroused global concerns, especially in the midst of pandemic COVID-19. Antimicrobial resistance has been accelerated by widespread usage of antimicrobial products in response to the COVID-19 pandemic. Furthermore, the widespread use of antimicrobial products releases biohazardous substances into the environment, endangering the ecology and ecosystem. Therefore, several strategies or measurements are needed to tackle this problem. In this review, types of antimicrobial available, emerging nanotechnology in antimicrobial production and their advanced application have been discussed. The problem of antimicrobial resistance (AMR) due to antibiotic-resistant bacteria (ARB)and antimicrobial resistance genes (AMG) had become the biggest threat to public health. To deal with this problem, an in-depth discussion of the challenges faced in antimicrobial mitigations and potential alternatives was reviewed.

Keywords: Antimicrobial resistance; COVID-19; Mitigation strategies; Precision medication.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors
Anti-Bacterial Agents / pharmacology
Anti-Infective Agents*
COVID-19*
Drug Resistance, Bacterial
Ecosystem
Humans
Pandemics / prevention & control

Substances

Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors
Anti-Bacterial Agents
Anti-Infective Agents