Transcranial ultrasound simulations: A review

Med Phys. 2023 Feb;50(2):1051-1072. doi: 10.1002/mp.15955. Epub 2022 Sep 12.

Abstract

Transcranial ultrasound is more and more used for therapy and imaging of the brain. However, the skull is a highly attenuating and aberrating medium, with different structures and acoustic properties among samples and even within a sample. Thus, case-specific simulations are needed to perform transcranial focused ultrasound interventions safely. In this article, we provide a review of the different methods used to model the skull and to simulate ultrasound propagation through it.

Keywords: CT-scan acoustical properties; skull acoustical properties; skull modeling; transcranial acoustic simulations; transcranial ultrasound focusing; transcranial ultrasound simulations.

Publication types

  • Review

MeSH terms

  • Acoustics
  • Brain* / diagnostic imaging
  • Computer Simulation
  • Skull* / diagnostic imaging
  • Ultrasonography / methods