[68Ga-DOTATOC PET/CT for Diagnosing Neuroendocrine Tumors]

Gan To Kagaku Ryoho. 2022 Aug;49(8):821-825.
[Article in Japanese]

Abstract

Lutathera is a peptide receptor radionuclide therapy (PRRT) for neuroendocrine tumors and was approved as the first PRRT drug in Japan in 2021. Although neuroendocrine tumors are often less aggressive than other highly malignant and invasive tumors, there have been few effective therapy options, so "Lutathera"is a long-awaited treatment. Lutathera is indicated for the treatment of "somatostatin receptor-positive neuroendocrine tumors". Currently, in Japan, the only imaging method to evaluate the expression of somatostatin receptors in lesions is scintigraphy using In-111 pentetreotide(OctreoScan). In this section, we would like to introduce the current status of the 68Ga-DOTA-SSA PET/CT using somatostatin analogue(SSA)in our institution.

MeSH terms

  • Humans
  • Neuroendocrine Tumors* / diagnostic imaging
  • Octreotide / analogs & derivatives
  • Octreotide / therapeutic use
  • Organometallic Compounds*
  • Positron Emission Tomography Computed Tomography
  • Positron-Emission Tomography / methods
  • Radiopharmaceuticals

Substances

  • Ga(III)-DOTATOC
  • Organometallic Compounds
  • Radiopharmaceuticals
  • Octreotide