Case Report: Erroneous Human Immunodeficiency Virus-1 Diagnosis in a Pregnant Woman Using Centers for Disease Control and Prevention Diagnostic Algorithm

Elizabeth Hastie; Lisa Stangl; Karen Deutsch; Jeffrey Yin; Andrew Hull; Stephen A Spector; Jill Blumenthal

doi:10.1093/ofid/ofac402

Case Report: Erroneous Human Immunodeficiency Virus-1 Diagnosis in a Pregnant Woman Using Centers for Disease Control and Prevention Diagnostic Algorithm

Open Forum Infect Dis. 2022 Aug 9;9(8):ofac402. doi: 10.1093/ofid/ofac402. eCollection 2022 Aug.

Authors

Elizabeth Hastie¹, Lisa Stangl¹, Karen Deutsch¹, Jeffrey Yin¹, Andrew Hull¹, Stephen A Spector¹, Jill Blumenthal¹

Affiliation

¹ University of California San Diego, San Diego, California, USA.

Abstract

We describe a case of a pregnant cisgender woman diagnosed with human immunodeficiency virus (HIV)-1 using the current Centers for Disease Control and Prevention diagnostic algorithm who subsequently had her diagnosis overturned after additional testing outside of the algorithm, including an HIV-1 proviral deoxyribonucleic acid test that was negative.

Keywords: HIV; HIV-1 proviral DNA; antibody and p24 combination immunoassay; diagnostic algorithm; false positive.

Publication types

Case Reports

Grants and funding

UM1 AI069536/AI/NIAID NIH HHS/United States