The synthesis of deuteriated tri-tert-butyl phosphine

Lucy C Brown; Anne McGrogan; Yoan Delavoux; James M Hogg; John D Holbrey; H Q Nimal Gunaratne; Małgorzata Swadźba-Kwaśny; James P Tellam; Sarah E Youngs

doi:10.1002/jlcr.4001

The synthesis of deuteriated tri-tert-butyl phosphine

J Labelled Comp Radiopharm. 2022 Nov;65(13):338-342. doi: 10.1002/jlcr.4001. Epub 2022 Sep 5.

Authors

Lucy C Brown¹, Anne McGrogan¹, Yoan Delavoux¹, James M Hogg^{1

2}, John D Holbrey¹, H Q Nimal Gunaratne¹, Małgorzata Swadźba-Kwaśny¹, James P Tellam³, Sarah E Youngs³

Affiliations

¹ The QUILL Research Centre, School of Chemistry and Chemical Engineering, Queen's University Belfast, Belfast, UK.
² Department of Chemical Engineering, University of Bath, Bath, UK.
³ ISIS Neutron and Muon Source, Rutherford Appleton Laboratory, Harwell Campus, Didcot, UK.

Abstract

The synthesis of deuteriated tri-tert-butyl phosphine is reported. This synthesis is an adaptation of the known procedure for tri-tert-butyl phosphine via a Grignard intermediate.

Keywords: Grignard; PtBu3; perdeuteriated; perdeuteriated ligands; phosphine; phosphine frustrated Lewis pairs; transition metal catalysis; tri-tert-butyl phosphine.

MeSH terms

Molecular Structure
Phosphines*

Substances

phosphine
Phosphines