[From the nose to the ear: field cancerization via the Eustachian tube]

HNO. 2023 Mar;71(3):177-179. doi: 10.1007/s00106-022-01221-6. Epub 2022 Aug 29.
[Article in German]

Abstract

We report on the metachronic appearance of an inverted papilloma in the ipsilateral middle ear after resection of an endonasal inverted papilloma and its malignant transformation. After multiple surgical interventions and adjuvant radiation and chemotherapy, there was recurrence with intracerebral growth, which ultimately led to the patient's death 3 years after the initial presentation.

Wir berichten über das metachrone Auftreten eines invertierten Papilloms im ipsilateralen Mittelohr nach Resektion eines endonasalen invertierten Papilloms sowie über dessen maligne Transformation. Nach mehrfachen sanierenden Operationen sowie adjuvanter Radiochemotherapie kam es zu einem Rezidiv mit intrazerebraler Manifestation. Diese führte zum Tod der Patientin drei Jahre nach Erstvorstellung.

Keywords: Inverted papilloma; Middle ear carcinoma; Parotid gland; Radiation therapy; Recurrence.

Publication types

  • English Abstract

MeSH terms

  • Ear, Middle / pathology
  • Ear, Middle / surgery
  • Eustachian Tube* / surgery
  • Humans
  • Neoplasm Recurrence, Local
  • Nose / pathology
  • Nose Neoplasms* / diagnosis
  • Nose Neoplasms* / surgery
  • Papilloma, Inverted* / surgery