Efficient and Recyclable Solid-Supported Pd(II) Catalyst for Microwave-Assisted Suzuki Cross-Coupling in Aqueous Medium

Abdulrahman M Alazemi; Kamal M Dawood; Hamad M Al-Matar; Wael M Tohamy

doi:10.1021/acsomega.2c01809

Efficient and Recyclable Solid-Supported Pd(II) Catalyst for Microwave-Assisted Suzuki Cross-Coupling in Aqueous Medium

ACS Omega. 2022 Aug 10;7(33):28831-28848. doi: 10.1021/acsomega.2c01809. eCollection 2022 Aug 23.

Authors

Abdulrahman M Alazemi¹, Kamal M Dawood², Hamad M Al-Matar¹, Wael M Tohamy^{1

3}

Affiliations

¹ Chemistry Department, Faculty of Science, University of Kuwait, P.O. Box 5969, Safat 13060, Kuwait.
² Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt.
³ Organometallic and Organometalloid Chemistry Department, National Research Centre, Cairo 12622, Egypt.

Abstract

Solid-supported catalysts play efficient and crucial roles in organic synthesis. A solid-supported palladium(II) complex based on chitosan was synthesized and fully characterized using all possible tools (Fourier transform infrared spectroscopy, thermogravimetry analysis, differential scanning calorimetry, X-ray photoelectron spectroscopy, energy-dispersive X-ray spectroscopy, inductively coupled plasma atomic emission spectrometry, scanning electron microscopy, transmission electron microscopy, and Brunauer-Emmett-Teller analysis). The catalytic activity of the solid-phase catalyst in Suzuki cross-coupling reactions was evaluated in aqueous solvents under both conventional heating and microwave irradiation conditions. The recyclability and thermal stability of the prepared catalyst were also examined, and the catalyst was found to be active till five consecutive runs without a notable loss of activity under the microwave condition, with the turnover number and turnover frequency values reaching 19,019 and 114,114 h^-1, respectively.