Prognostic significance of smudge cell percentage in chronic lymphocytic leukemia. Facts or artifacts? Methodological considerations and literature review

Clin Chem Lab Med. 2022 Aug 29;60(11):e246-e249. doi: 10.1515/cclm-2022-0658. Print 2022 Oct 26.

Affiliations

¹ Laboratory Medicine, Docemus, Torrevecchia Teatina, Italy.
² Laboratorio Analisi Chimico-Cliniche Azienda Spedaliero-Universitaria Pisana, Pisa, Italy.
³ U.O. Patologia Clinica A.O.R.N. "G. Rummo", Benevento, Italy.
⁴ U.O.C. Medicina di Laboratorio "F. Lotti", Azienda Usl Nord Ovest, Pontedera, Italy.

PMID: 36030427
DOI: 10.1515/cclm-2022-0658

No abstract available

Keywords: Gumprecht shadows; chronic lymphocytic leukemia; peripheral blood microscopic review; smudge cells prognostic value.

Publication types

Letter
Review

MeSH terms

Artifacts
Humans
Leukemia, Lymphocytic, Chronic, B-Cell* / diagnosis
Lymphocyte Count
Lymphocytes
Prognosis