Pulsed electrical field in arrhythmia treatment: Current status and future directions

Pacing Clin Electrophysiol. 2022 Oct;45(10):1255-1262. doi: 10.1111/pace.14586. Epub 2022 Sep 8.

Abstract

Pulsed electrical field (PEF) ablation is a promising novel ablation modality for the treatment of arrhythmia, especially for atrial fibrillation (AF). There have been several important advances in PEF ablation over the past several years, such as the parameters of PEF delivery and electrode Design. And the results in almost all clinical studies of PEF for AF ablation are optimistic, both in terms of effectiveness and safety. This article provides a brief overview of the mechanism and technical progress of PEF ablation in cardiac arrhythmia treatment, and discuss it's potential applications and the future development.

Keywords: atrial fibrillation; irreversible electroporation; pulsed electrical field.

Publication types

  • Review

MeSH terms

  • Atrial Fibrillation* / surgery
  • Catheter Ablation* / methods
  • Humans
  • Pulmonary Veins* / surgery
  • Treatment Outcome