Guide of management of alterations in mineral and bone metabolism during gestation and lactation

Abstract

Objective: To provide practical recommendations for the management of mineral and bone metabolism alterations in pregnancy and lactation.

Participants: Members of the Working Group on Osteoporosis and Mineral Metabolism of the Spanish Society of Endocrinology and Nutrition.

Methods: Recommendations were formulated according to the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence. A systematic search was carried out in Medline of the available evidence for each pathology. Papers in English with publication date until 29 February 2020 were included. A methodologist resolved the differences that arose during the process of reviewing the literature and formulating recommendations. The recommendations were discussed and approved by all members of the Working Group.

Conclusions: The document establishes practical recommendations based on evidence about the management of mineral and bone metabolism disorders in pregnancy and lactation.

Keywords: Chronic hypoparathyroidism; Embarazo; Fracturas; Fractures; Hiperparatiroidismo primario; Hipoparatiroidismo crónico; Hipovitaminosis D; Hypovitaminosis D; Lactancia; Lactation; Osteoporosis; Pregnancy; Primary hyperparathyroidism.