1 Faculty of Medicine, Université Paris-Saclay, Le Kremlin-Bicêtre, France, Service de Pneumologie et Soins Intensifs Respiratoires, Centre de Référence de l'Hypertension Pulmonaire, Hôpital Bicêtre, Assistance Publique Hôpitaux de Paris, Le Kremlin-Bicêtre, France.
2 INSERM UMR_S 999, Hôpital Marie-Lannelongue, Le Plessis-Robinson, France.
3 University Clinic of Internal Medicine, Division of Pulmonology, Medical University of Graz, Graz, Austria.
4 Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
5 Respiratory Medicine, Hannover Medical School, Hanover, Germany.
6 Biomedical Research in End-stage and Obstructive Lung Disease (BREATH), member of the German Centre of Lung Research (DZL), Hanover, Germany.
7 Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma, Roma, Italy.
8 Dipartimento Cardio-Toraco-Vascolare e Chirurgia dei Trapianti d'Organo, Policlinico Umberto I, Roma, Italy.
9 Center for Congenital Heart Diseases, Beatrix Children's Hospital, Dept of Paediatric Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
10 Department of Sports and Rehabilitation Medicine, Medical Faculty University of Rijeka, Rijeka, Croatia.
11 Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton and Harefield Hospitals, Guys and St Thomas's NHS Trust, London, UK.
12 Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
13 Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
14 Faculty of Medicine, University of Warwick, Coventry, UK.
15 Faculty of Medicine, Monash University, Melbourne, Australia.
16 Pulmonary Hypertension Unit, Cardiology Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
17 CIBER-CV (Centro de Investigaciones Biomédicas En Red de enfermedades CardioVasculares), Instituto de Salud Carlos III, Madrid, Spain.
18 Facultad de Medicina, Universidad Complutense, Madrid, Spain.
19 ESC Patient Forum, Sophia Antipolis, France.
20 AIPI, Associazione Italiana Ipertensione Polmonare, Bologna, Italy.
21 Alergia e Imunologia, Hospital de Clinicas, Universidade Federal do Parana, Curitiba, Brazil.
22 Department of Internal Medicine, University Hospital Giessen, Justus-Liebig University, Giessen, Germany.
23 Department of Pneumology, Kerckhoff Klinik, Bad Nauheim, Germany.
24 Department of Medicine, Imperial College London, London, UK.
25 Cardiology Department, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece.
26 Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.
27 Sheffield Pulmonary Vascular Disease Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
28 Insigneo Institute, University of Sheffield, Sheffield, UK.
29 Thoracic Surgery, Kerckhoff Clinic, Bad Nauheim, Germany.
30 European Lung Foundation (ELF), Sheffield, UK.
31 Institute for Evidence in Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
32 Clinic of Respiratory Medicine, Hannover Medical School, member of the German Center of Lung Research (DZL), Hannover, Germany.
33 Pulmonary Vascular Diseases Unit, Royal Papworth Hospital, Cambridge, UK.
34 NHLI, Imperial College London, London, UK.
35 Department of Cardiology, Clinical Sciences Lund, Faculty of Medicine, Lund, Sweden.
36 The Haemodynamic Lab, The Section for Heart Failure and Valvular Disease, VO. Heart and Lung Medicine, Skåne University Hospital, Lund, Sweden.
37 Faculté Médecine, Université Paris Saclay, Le Kremlin-Bicêtre, France.
38 Centre de Référence de l'Hypertension Pulmonaire, Hopital Marie-Lannelongue, Le Plessis-Robinson, France.
39 Service de Pneumologie et Soins Intensifs Respiratoires, Centre de Référence de l'Hypertension Pulmonaire, Hôpital Bicêtre, Assistance Publique Hôpitaux de Paris, Le Kremlin-Bicêtre, France.
40 Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
41 Dept of Medicine, Heart Lung Research Institute, University of Cambridge, Royal Papworth NHS Trust, Cambridge, UK.
42 Department of Cardiology, Pulmonary Vascular Diseases and Heart Failure Clinic, HUB Hôpital Erasme, Brussels, Belgium.
43 Pulmonology, Amsterdam UMC, Amsterdam, The Netherlands.
44 Clinical Department of Respiratory Diseases, Centre of Pulmonary Vascular Diseases, University Hospitals of Leuven, Leuven, Belgium.
45 The two chairpersons (M. Delcroix and S. Rosenkranz) contributed equally to the document and are joint corresponding authors.
46 Clinic III for Internal Medicine (Department of Cardiology, Pulmonology and Intensive Care Medicine), and Cologne Cardiovascular Research Center (CCRC), Heart Center at the University Hospital Cologne, Köln, Germany stephan.rosenkranz@uk-koeln.de marion.delcroix@uzleuven.be.