Background: Body mass index (BMI) is positively associated with the risk of colorectal cancer (CRC). For that reason, investigators have hypothesized that being overweight or obese leads to worse CRC prognosis and survival outcome.
Methodology: The impact of BMI in patients with colorectal cancer on (disease free survival) DFS and three years overall survival (OS) rates in correlation with clinic-pathological data of those patients was studied on 128 patients enrolled in this study. They were diagnosed with stage II and III colorectal cancer that presented at clinical oncology department Ain Shams University hospitals from January 2016 till December 2017 with 3 years duration follow up. All of them had measured their BMI at time of presentation.
Results: Estimated 3- years OS for each BMI category revealed that normal weight patients had 97.1% survival rate and overweight patients had 77.8% survival rate. Much lower survival rates for both underweight and obese patients had been estimated being (33.3%, 37.3%) respectively. This correlation to BMI categories shows a statistically significant value between normal weight patients and overweight patients in relation to underweight and obese patients (p- value < 0.0001).
Conclusion: BMI has an impact on colorectal cancer patients with clinicopathological relations and survival rate.
Keywords: Body mass index; Colorectal cancer (CRC); Disease- free survival (DFS); Overall survival (OS).
Copyright © 2022. Published by Elsevier Ltd.