Transcriptional Factors and Epigenetic Mechanisms in Obesity and Related Metabolic Comorbidities

Cells. 2022 Aug 14;11(16):2520. doi: 10.3390/cells11162520.

Abstract

Recent advances in the study of chromatin remodeling and transcriptional machinery complex dysfunction, and how they drive metabolic-related gene expression have considerably increased our understanding of several molecular processes underlaying obesity and its complications [...].

Keywords: DNA methylation; circular RNAs; gene expression; high fat diet; metabolic diseases; noncoding RNAs; type 2 diabetes.

Publication types

  • Editorial

MeSH terms

  • Comorbidity
  • DNA Methylation
  • Epigenesis, Genetic*
  • Humans
  • Obesity / metabolism
  • Transcription Factors* / metabolism

Substances

  • Transcription Factors

Grants and funding

The research received no external finding.