αβT- and B-cell-depleted HLA-haploidentical hematopoietic stem cell transplantation in children with myelodysplastic syndromes

Pietro Merli; Daria Pagliara; Tommaso Mina; Valentina Bertaina; Giuseppina Li Pira; Stefania Lazzaro; Simone Biagini; Federica Galaverna; Luisa Strocchio; Roberto Carta; Maria Luigia Catanoso; Francesco Quagliarella; Marco Becilli; Emilia Boccieri; Francesca Del Bufalo; Arianna Panigari; Annalisa Agostini; Lucia Pedace; Simone Pizzi; Cesare Perotti; Mattia Algeri; Marco Zecca; Franco Locatelli

doi:10.3324/haematol.2022.280698

αβT- and B-cell-depleted HLA-haploidentical hematopoietic stem cell transplantation in children with myelodysplastic syndromes

Haematologica. 2022 Dec 1;107(12):2966-2971. doi: 10.3324/haematol.2022.280698.

Authors

Pietro Merli¹, Daria Pagliara², Tommaso Mina³, Valentina Bertaina², Giuseppina Li Pira², Stefania Lazzaro⁴, Simone Biagini², Federica Galaverna², Luisa Strocchio², Roberto Carta², Maria Luigia Catanoso², Francesco Quagliarella², Marco Becilli², Emilia Boccieri², Francesca Del Bufalo², Arianna Panigari³, Annalisa Agostini³, Lucia Pedace², Simone Pizzi⁵, Cesare Perotti⁶, Mattia Algeri², Marco Zecca⁷, Franco Locatelli⁸

Affiliations

¹ Department of Pediatric Hematology/Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, Rome. pietro.merli@opbg.net.
² Department of Pediatric Hematology/Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, Rome.
³ Pediatric Hematology-Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia.
⁴ Transfusion Unit, Department of Laboratories, Bambino Gesù Children's Hospital, IRCCS, Rome.
⁵ Genetics and Rare Diseases Research Division, Bambino Gesù Children's Hospital, IRCCS, Rome.
⁶ Departments of Immunohematology and Transfusion, Infectious Diseases, Respiratory Diseases, Intensive Care, Virology and Clinical Epidemiology and Biometry, Fondazione IRCCS Policlinico San Matteo, Pavia.
⁷ Pediatric Hematology/Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia.
⁸ Department of Pediatric Hematology/Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy; Sapienza, University of Rome, Rome.

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Letter

MeSH terms

B-Lymphocytes
Child
Graft vs Host Disease*
Hematopoietic Stem Cell Transplantation*
Humans
Myelodysplastic Syndromes* / therapy

Grants and funding

Funding: his work was partially supported by grants from Italian Ministry of Health (GR-2011-02350175 to PM) and from the Associazione Italiana Ricerca sul Cancro, (Investigator Grant ID 21724 to FL).