EGFR blockade confers sensitivity to cabozantinib in hepatocellular carcinoma

Cell Discov. 2022 Aug 23;8(1):82. doi: 10.1038/s41421-022-00425-y.

Xuhui Ma^#¹, Shanshan Wu^#¹, Botai Li^#^{1

2}, Qianqian Zhang³, Jianming Zhang³, Wenming Liu^{4

5}, Hexin Yan^{1

4

5}, René Bernards^{6

7}, Wenxin Qin⁸, Cun Wang⁹

¹ State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
² Shanghai Immune Therapy Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
³ National Research Center for Translational Medicine (Shanghai), State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁴ Department of Anesthesiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁵ Shanghai Engineering Research Center of Peri-Operative Organ Support and Function Preservation Shanghai, Shanghai, China.
⁶ State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. r.bernards@nki.nl.
⁷ Division of Molecular Carcinogenesis, Oncode Institute. The Netherlands Cancer Institute, Amsterdam, The Netherlands. r.bernards@nki.nl.
⁸ State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. wxqin@sjtu.edu.cn.
⁹ State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. cwang@shsci.org.

^# Contributed equally.

No abstract available

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