International Spread of Multidrug-Resistant Rhodococcus equi

Emerg Infect Dis. 2022 Sep;28(9):1899-1903. doi: 10.3201/eid2809.220222.

Abstract

A multidrug-resistant clone of the animal and human pathogen Rhodococcus equi, MDR-RE 2287, has been circulating among equine farms in the United States since the 2000s. We report the detection of MDR-RE 2287 outside the United States. Our finding highlights the risk for MDR-RE spreading internationally with horse movements.

Keywords: MDR R. equi; MDR-RE; R. equi MDR 2287 clone; Rhodococcus equi; TnRErm46; United States; antimicrobial resistance; bacteria; erm(46); macrolide resistance; multidrug-resistant Rhodococcus equi; pRErm46; rifampin resistance; zoonoses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actinomycetales Infections* / drug therapy
  • Actinomycetales Infections* / epidemiology
  • Actinomycetales Infections* / veterinary
  • Animals
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Drug Resistance, Bacterial
  • Horse Diseases* / epidemiology
  • Horses
  • Humans
  • Macrolides
  • Rhodococcus equi* / genetics
  • Rifampin
  • United States

Substances

  • Anti-Bacterial Agents
  • Macrolides
  • Rifampin

Supplementary concepts

  • Rhodococcus hoagii