Prevalence and risk factors of untreated thyroid dysfunctions in the older Caucasian adults: Results of PolSenior 2 survey

PLoS One. 2022 Aug 22;17(8):e0272045. doi: 10.1371/journal.pone.0272045. eCollection 2022.

Abstract

Introduction: To determine the prevalence of treated and untreated thyroid dysfunction and to identify factors associated with increased risk of undiagnosed thyroid dysfunction in older adults.

Methods: The population of 5987 community-dwelling Polish Caucasian seniors aged 60 years and above who participated in the PolSenior 2 study (2018-2019). Population-based cross-sectional multidisciplinary study in design. Data from structured questionnaires, geriatric tests, and scales were obtained from all study participants who underwent anthropometric and blood pressure measurements during three home visits. Assessment of thyroid function was based on TSH serum measurements.

Results: The prevalence of thyroid dysfunction in the Polish population aged 60 years or above was estimated at 15.5% (21.5% in women and 7.2% in men), with 3.2% of undiagnosed individuals among them. The prevalence of hypothyroidism and hyperthyroidism in the studied group was 13.9% (19.4% in women and 6.3% in men) and 1.6% (2.1% in women and 0.9% in men) respectively, untreated hypothyroidism was revealed in 21.9% (in 160 out of 732 subjects) and untreated hyperthyroidism in 34.2% of subjects (in 41 out of 120 participants). In multiple regression analysis independent risk factors for thyroid disorders being untreated were older age (> 75 years), male sex, a low education level (primary or lower), and low utilization of medical services.

Conclusions: One-fifth of Polish Caucasian seniors with hypothyroidism and one-third with hyperthyroidism are untreated. Older, poorly educated and rarely utilizing medical services seniors, especially men, are more frequently untreated for thyroid dysfunction and some of them do not benefit from contemporary achievements in medicine.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hyperthyroidism* / epidemiology
  • Hypothyroidism* / epidemiology
  • Male
  • Prevalence
  • Risk Factors
  • Surveys and Questionnaires
  • Thyroid Diseases* / epidemiology
  • Thyrotropin

Substances

  • Thyrotropin

Grants and funding

This paper was implemented under contract No. 6/5 / 4.2 / NPZ / 2017/1203/1257 for the implementation of the task in the field of public health of the Operational Objective No. 5 points 4.2. of the National Health Program for years 2016-2020, entitled "Health Status and Its Socio-economic Covariates of the Older Population in Poland - the Nationwide PolSenior2 Survey" (PolSenior2). The funders had no role in study design, data collection and analysis, decision to publish, or reparation of the manuscript.