Primary Localized Cutaneous Nodular Amyloidosis Presenting as Milia: An Unusual Clinical Manifestation

Clin Cosmet Investig Dermatol. 2022 Aug 13:15:1639-1642. doi: 10.2147/CCID.S378253. eCollection 2022.

Abstract

Primary localized cutaneous nodular amyloidosis (PLCNA) is rare and clinically noncharacteristic, presenting mostly as plaque-like lesions. We report a case of a progressively larger erythematous plaque following a contusion of the skin on the right zygomatic area, which was strangely covered with recurrent scattered 2 mm whiteish blisters to the extent that it was misdiagnosed as a herpesvirus infection several times over a decade. Pathology and special staining diagnosed nodular amyloidosis with milia.

Keywords: local trauma; milia; plaque; primary localized cutaneous nodular amyloidosis.

Publication types

  • Case Reports