The deep learning methods for various disease prediction tasks have become very effective and even surpass human experts. However, the lack of interpretability and medical expertise limits its clinical application. This paper combines knowledge representation learning and deep learning methods, and a disease prediction model is constructed. The model initially constructs the relationship graph between the physical indicator and the test value based on the normal range of human physical examination index. And the human physical examination index for testing value by knowledge representation learning model is encoded. Then, the patient physical examination data is represented as a vector and input into a deep learning model built with self-attention mechanism and convolutional neural network to implement disease prediction. The experimental results show that the model which is used in diabetes prediction yields an accuracy of 97.18% and the recall of 87.55%, which outperforms other machine learning methods (e.g., lasso, ridge, support vector machine, random forest, and XGBoost). Compared with the best performing random forest method, the recall is increased by 5.34%, respectively. Therefore, it can be concluded that the application of medical knowledge into deep learning through knowledge representation learning can be used in diabetes prediction for the purpose of early detection and assisting diagnosis.
Copyright © 2022 He Xu et al.