Copper-containing nanoparticles: Mechanism of antimicrobial effect and application in dentistry-a narrative review

Xinru Ma; Shiyu Zhou; Xiaoling Xu; Qin Du

doi:10.3389/fsurg.2022.905892

Copper-containing nanoparticles: Mechanism of antimicrobial effect and application in dentistry-a narrative review

Front Surg. 2022 Aug 5:9:905892. doi: 10.3389/fsurg.2022.905892. eCollection 2022.

Authors

Xinru Ma^{1

2}, Shiyu Zhou¹, Xiaoling Xu³, Qin Du¹

Affiliations

¹ Department of Stomatology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
² Department of Stomatology, Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region (West China Hospital Sichuan University Tibet Chengdu Branch Hospital), Chengdu, China.
³ School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, China.

Abstract

Copper has been used as an antimicrobial agent long time ago. Nowadays, copper-containing nanoparticles (NPs) with antimicrobial properties have been widely used in all aspects of our daily life. Copper-containing NPs may also be incorporated or coated on the surface of dental materials to inhibit oral pathogenic microorganisms. This review aims to detail copper-containing NPs' antimicrobial mechanism, cytotoxic effect and their application in dentistry.

Keywords: antimicrobial effect; candida albicans; copper nanoparticles; oral pathogen; porphyromonas gingivalis; streptococcus mutans.

Publication types

Review