Electrospun Nanofibers for Wound Management

ChemNanoMat. 2022 Jul;8(7):e202100349. doi: 10.1002/cnma.202100349. Epub 2021 Nov 1.

Abstract

Electrospun nanofibers show great potential in biomedical applications. This mini review article traces the recent advances in electrospun nanofibers for wound management via various approaches. Initially, we provide a short note on the four phases of wound healing, including hemostasis, inflammation, proliferation, and remodeling. Then, we state how the nanofiber dressings can stop bleeding and reduce the pain. Following that, we discuss the delivery of therapeutics and cells using different types of nanofibers for enhancing cell migration, angiogenesis, and re-epithelialization, resulting in the promotion of wound healing. Finally, we present the conclusions and future perspectives regarding the use of electrospun nanofibers for wound management.

Keywords: Antibacterial; Electrospun nanofibers; Hemostasis; Pain relief; Wound healing.