Brain Surgery for Medically Intractable Epilepsy

Vincent Joris; Alexander G Weil; Aria Fallah

doi:10.1016/j.yapd.2022.03.014

Brain Surgery for Medically Intractable Epilepsy

Adv Pediatr. 2022 Aug;69(1):59-74. doi: 10.1016/j.yapd.2022.03.014. Epub 2022 Jun 20.

Authors

Vincent Joris¹, Alexander G Weil², Aria Fallah³

Affiliations

¹ Fellow, Department of Neurosurgery, Sainte-Justine University Hospital Centre, 3175 Chemin de la Côte-Sainte-Catherine, Montreal, Quebec H3T 1C5, Canada.
² Associate Professor, Department of Neurosurgery, Sainte-Justine University Hospital Centre, 3175 Chemin de la Côte-Sainte-Catherine, Montreal, Quebec H3T 1C5, Canada.
³ Associate Professor, Department of Neurosurgery, David Geffen School of Medicine at University of California, Los Angeles, 300 Stein Plaza, Suite 525, Los Angeles, CA 90095, USA. Electronic address: afallah@mednet.ucla.edu.

PMID: 35985717
DOI: 10.1016/j.yapd.2022.03.014

Abstract

This review covers the broad topic of brain surgery in the treatment of pediatric intractable epilepsy. The authors review the latest advancements in the presurgical workup as well as the mandatory tests needed to explore the epilepsy workup in these children. They describe the different types of epilepsy from a surgical standpoint (temporal, extratemporal, multifocal, and hemispheric epilepsies) and various surgical procedures that can be proposed depending on the clinical scenario: lesionectomies, lobectomies, hemispherectomies, neuromodulation, and palliative surgeries. They also describe the key differences of the pediatric patient as compared with the adult patient in such pathologic conditions.

Keywords: Epilepsy surgery; Medically intractable epilepsy; Outcomes; Resection; Surgical selection.

Publication types

Review

MeSH terms

Adult
Brain / diagnostic imaging
Brain / surgery
Child
Drug Resistant Epilepsy* / diagnosis
Drug Resistant Epilepsy* / surgery
Epilepsy* / diagnosis
Epilepsy* / surgery
Humans
Treatment Outcome