Natural language processing (NLP) plays a key role in advancing health care, being key to extracting structured information from electronic health reports. In the last decade, several advances in the field of pathology have been derived from the application of NLP to pathology reports. Herein, a comprehensive review of the most used NLP methods for extracting, coding, and organizing information from pathology reports is presented, including how the development of tools is used to improve workflow. In addition, this article discusses, from a practical point of view, the steps necessary to extract data and encode natural language information for its analytical processing, ranging from preprocessing of text to its inclusion in complex algorithms. Finally, the potential of NLP-based automatic solutions for improving workflow in pathology and their further applications in the near future is highlighted.
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