Death due to unsuspected acute myeloid leukaemia: an unusual forensic diagnosis

Forensic Sci Med Pathol. 2023 Mar;19(1):60-66. doi: 10.1007/s12024-022-00516-y. Epub 2022 Aug 19.

Abstract

Acute myeloid leukaemia (AML) is a rare haematologic cancer with a rapid increase in blast cells, which need to be rapidly diagnosed and treated. The aim of this report is to analyse the rare phenomenon of AML diagnosed at autopsy after sudden death. We report three cases of AML and perform a literature review using the mesh terms "sudden death" and "leukaemia". We report the cases of three young women diagnosed with AML only after autopsy. We found seven articles which reported sudden death due to AML diagnosed at autopsy. Diagnosis of AML during autopsy is rare but can raise forensic issues. A complete autopsy with pathology analysis is needed.

Keywords: Autopsy; Brain haemorrhage; Death; Leukaemia; Pathology.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Autopsy
  • Cause of Death
  • Female
  • Forensic Medicine
  • Humans
  • Leukemia, Myeloid, Acute* / diagnosis
  • Leukemia, Myeloid, Acute* / pathology
  • Male
  • Middle Aged
  • Young Adult