Gynaecological management of women with inherited bleeding disorders. A UK Haemophilia Centres Doctors' Organisation Guideline

Haemophilia. 2022 Nov;28(6):917-937. doi: 10.1111/hae.14643. Epub 2022 Aug 17.

Abstract

Women with inherited bleeding disorders (IBDs) may present to healthcare professionals in a variety of ways and commonly will be encountered by either haematology or gynaecology services. Heavy menstrual bleeding is very often the first manifestation of an IBD. There is a wide variation in severity of bleeding for women with IBD and diagnosis and subsequent management of their condition requires multidisciplinary specialised care which is tailored to the individual and includes excellent cross-specialty communication between gynaecology and haematology teams. This guideline is intended for both haematologists and gynaecologists who are involved in the diagnosis and management of women with bleeding disorders. It sets out recommendations about how to investigate heavy menstrual bleeding (HMB), the commonest presentation for women with IBD to hospital services, to guide physicians about how to diagnose an IBD and covers the management of women with known IBD and HMB. The second section sets out recommendations for patients known to have IBD and covers management of patients with IBD in the setting of gynaecological surgery and management for all other non-surgical gynaecological situations.

Keywords: gynaecological management; gynaecological surgery; heavy menstrual bleeding; inherited bleeding disorder and fertility; inherited bleeding disorders; ovulation-related bleeding.

Publication types

  • Review

MeSH terms

  • Female
  • Gynecology*
  • Hemophilia A* / diagnosis
  • Hemophilia A* / therapy
  • Humans
  • Inflammatory Bowel Diseases* / complications
  • Inflammatory Bowel Diseases* / diagnosis
  • Inflammatory Bowel Diseases* / therapy
  • Menorrhagia* / diagnosis
  • Menorrhagia* / etiology
  • Menorrhagia* / therapy
  • Physicians*
  • United Kingdom