Trajectory of livestock genomics in South Asia: A comprehensive review

Gene. 2022 Nov 15:843:146808. doi: 10.1016/j.gene.2022.146808. Epub 2022 Aug 13.

Abstract

Livestock plays a central role in sustaining human livelihood in South Asia. There are numerous and distinct livestock species in South Asian countries. Several of them have experienced genetic development in recent years due to the application of genomic technologies and effective breeding programs. This review discusses genomic studies on cattle, buffalo, sheep, goat, pig, horse, camel, yak, mithun, and poultry. The frontiers covered in this review are genetic diversity, admixture studies, selection signature research, QTL discovery, genome-wide association studies (GWAS), and genomic selection. The review concludes with recommendations for South Asian livestock systems to increasingly leverage genomic technologies, based on the lessons learned from the numerous case studies. This paper aims to present a comprehensive analysis of the dichotomy in the South Asian livestock sector and argues that a realistic approach to genomics in livestock can ensure long-term genetic advancements.

Keywords: Genomics; Livestock; Next-generation sequencing; SNP; South-Asia.

Publication types

  • Review

MeSH terms

  • Animals
  • Asia
  • Cattle / genetics
  • Genome
  • Genome-Wide Association Study*
  • Genomics
  • Goats / genetics
  • Horses / genetics
  • Humans
  • Livestock* / genetics
  • Sheep / genetics
  • Swine