[Hematological pathologies: the most successful model of de-escalation in radiotherapy]

Abstract

The proportion of patients irradiated in the context of malignant hematological pathologies decreased over the last decades. The main causes are the late side effects of the historical series and the new therapeutic strategies aiming to relay radiotherapy to the rank of option. At the same time, radiotherapy has been modernised, target volumes and total doses have been drastically reduced. Hodgkin's lymphomas, indolent follicular lymphomas and primary cerebral lymphomas are the main witnesses of this therapeutic deflation.

Keywords: De-escalation; Désescalade; Follicular lymphoma; Hodgkin's disease; Lymphome cérébral primitif; Lymphome folliculaire; Maladie de Hodgkin; Primary cerebral lymphoma.