Neuropsychology of temporal lobe epilepsies

Handb Clin Neurol. 2022:187:519-529. doi: 10.1016/B978-0-12-823493-8.00012-2.

Abstract

This chapter focuses on the neuropsychology of adults with temporal lobe epilepsy (TLE). First, a thorough description of the brain-behavior relationship characterizing focal TLE with and without hippocampal sclerosis is presented. Then, the aim and the specificity of the NPA in the care of epilepsy are described. Considering the high frequency of medically intractable TLE that can be treated by surgery, an assessment carried out in the context of pre- and postoperative evaluation is presented and discussed in light of insights from functional neuroimaging findings. Finally, we propose concluding remarks about the place of neuropsychology in the care of epilepsy in improving our understanding of the cognitive and emotional phenotypes associated with TLE.

Keywords: Assessment; Cognition; Emotion; Language; Memory; Mood; Surgery; Temporal lobe epilepsy; neuropsychology.

Publication types

  • Review

MeSH terms

  • Brain / diagnostic imaging
  • Epilepsy*
  • Epilepsy, Temporal Lobe* / diagnostic imaging
  • Epilepsy, Temporal Lobe* / surgery
  • Humans
  • Neuropsychology