Phenylpropanoids from Brachybotrys paridiformis maxim. Ex oliv. And their anti-HBV activities (II)

Si-Tong Wu; Fei Li; Yi-Xiao Wang; Bai-Hong Yu; Chun-Liu Ma; He-Qin Qiu; Guang-Shu Wang

doi:10.1016/j.phytochem.2022.113364

Phenylpropanoids from Brachybotrys paridiformis maxim. Ex oliv. And their anti-HBV activities (II)

Phytochemistry. 2022 Nov:203:113364. doi: 10.1016/j.phytochem.2022.113364. Epub 2022 Aug 10.

Authors

Si-Tong Wu¹, Fei Li², Yi-Xiao Wang¹, Bai-Hong Yu¹, Chun-Liu Ma¹, He-Qin Qiu¹, Guang-Shu Wang³

Affiliations

¹ School of Pharmaceutical Sciences, Jilin University, Changchun, 130021, People's Republic of China.
² School of Science and Technology, Huzhou College, Huzhou, 313000, People's Republic of China.
³ School of Pharmaceutical Sciences, Jilin University, Changchun, 130021, People's Republic of China. Electronic address: wgs@jlu.edu.cn.

PMID: 35963293
DOI: 10.1016/j.phytochem.2022.113364

Abstract

Five undescribed phenylpropanoids, one undescribed phenolic glucoside, and sixteen known compounds were isolated from Brachybotrys paridiformis Maxim. Ex Oliv. The undescribed compounds were named brachoside B-C, brach acid A-B, brachnan A, and brachin D, respectively. Additionally, the anti-hepatitis B virus activities of all isolated compounds were studied. Among them, brachnan A, brach acid A, globoidnan A, 3-carboxy-6,7-dihydroxy-1-(3',4'-dihydroxy-phenyl)-naphthalene, and 3,4-dihydroxybenzaldehyde showed significant anti-hepatitis B virus activities.

Keywords: Anti-HBV activity; Boraginaceae; Brachybotrys paridiformis; Phenylpropanoids.

MeSH terms

Boraginaceae*
Glucosides
Hepatitis B virus
Naphthalenes
Plant Extracts

Substances

Glucosides
Naphthalenes
Plant Extracts