We report detection of cases of monkeypox virus infection in Argentina in the context of a marked increase in confounding cases of atypical hand-foot-and-mouth syndrome caused by enterovirus coxsackie A6. We recommend performing an accurate differential virological diagnosis for exanthematous disease in suspected monkeypox cases.
Keywords: A6; Argentina; Bolivia; atypical hand-foot-mouth syndrome; enterovirus coxsackie; monkeypox; sexually transmitted infections; viruses.